Remerciez-le!

Remerciez @Admin pour avoir partagé cet document gratuitement, de la manière la plus simple, en partageant sur les réseaux sociaux.

Ngs application guide Next-Generation Sequencing Application Guide CApplications Illumina o ?ers standard options and features the NeoPrep System for reproducible sequencingready libraries with just minutes of hands-on time per run Sequencing With power f

Next-Generation Sequencing Application Guide CApplications Illumina o ?ers standard options and features the NeoPrep System for reproducible sequencingready libraries with just minutes of hands-on time per run Sequencing With power for every scale Illumina provides a complete portfolio of next-generation sequencing NGS solutions that are accessible for every study and every lab Informatics Intuitive informatics tools enable critical insights Essential data can be securely transferred stored analyzed and shared in BaseSpace Onsite or in the BaseSpace Cloud CApplications Instruments APPLICATIONS Whole-genome sequencing large genomes Whole- genome sequencing small genomes Whole-genome sequencing long- range Epigenetics Amplicon sequencing Cancer research sequencing panels Disease and condition sequencing panels Exome sequencing Metagenomics mRNA sequencing Whole transcriptome sequencing FFPE RNA sequencing Single-cell RNA sequencing Targeted RNA sequencing Ribosome pro ?le sequencing Micro RNA sequencing NeoPrep Library Prep System High-throughput library prep automation INSTRUMENTS MiSeq MiSeqDx NextSeq HiSeq HiSeq X Ten ANALYSIS TOOLS Push-button bioinformatics Analysis Tools A global genomics leader Illumina provides complete sample-to-answer solutions to the research and clinical communities Illumina technology is responsible for generating of the sequencing data in the world Through collaborative innovation Illumina is fueling groundbreaking advancements in the ?elds of oncology reproductive health genetic disease microbiology agriculture and forensic science customerservice illumina com ? option For Research Use Only www illumina com CApplications Applications For Research Use Only Next-Generation Sequencing Application Guide techsupport illumina com ? option Ccustomerservice illumina com ? option For Research Use Only www illumina com Applications CApplications DNA Whole-genome sequencing large genomes Resequence whole genomes and identify variants of interest for disease and population-level studies Key strengths ? Combines short inserts and longer reads to allow characterization of any genome ? Provides high-quality long contig assemblies for de novo whole-genome sequencing ? Reveals disease-causing alleles that might not have been identi ?ed otherwise ? Captures results for new variants without requiring resequencing LIBRARY PREP SEQUENCING TruSeq DNA PCR-Free N Sample Preparation Kit TruSeq Nano DNA Sample N Preparation Kit Nextera DNA Sample Preparation Kit NextSeq sample HiSeq ?? samples HiSeq X Ten up to genomes year ANALYSIS TOOLS If analyzed in BaseSpace Align Call variants BWA Whole Genome Seq Isaac Whole Genome Seq Tumor-Normal Seq Annotate Filter VariantStudio Visualize The Broad's IGV The combination of short inserts and longer reads allows characterization of any genome N NeoPrep version available ??see page Visit www illumina com largeWG for more details For Research Use Only Next-Generation Sequencing Application Guide techsupport illumina com ? option CApplications DNA Innovation Discovery Application Cancer research In cancer whole- genome sequencing can be employed to monitor genomic changes that occur in a tumor including the presence of markers for good and poor prognosis Through tumor-normal whole-genome sequencing researchers can identify the tumor genome and determine di ?erences from non-tumor DNA Complex disease Next-generation sequencing NGS is proving to be a powerful tool for genomewide association studies GWAS GWAS allows researchers to identify common genetic variants across populations to establish links between those variants and the traits of individuals including predisposition to disease