Remerciez-le!

Remerciez @Admin pour avoir partagé cet document gratuitement, de la manière la plus simple, en partageant sur les réseaux sociaux.

Mrcpch guide inf MRCPCH GUIDE Inf Varicella ??zoster immunoglobulin VZIG is recommended for individuals who are at increased risk of severe varicella and who have no antibodies to varicella ??zoster virus and who have signi ?cant exposure to chickenpox or

MRCPCH GUIDE Inf Varicella ??zoster immunoglobulin VZIG is recommended for individuals who are at increased risk of severe varicella and who have no antibodies to varicella ??zoster virus and who have signi ?cant exposure to chickenpox or herpes zoster Those at increased risk include neonates of women who develop chickenpox in the period days before to days after delivery women exposed at any stage of pregnancy and the immunosuppressed including those who have received corticosteroids in the previous months at the following dose equivalents of prednisolone mg kg day for at least week or mg kg day for month Universal BCG immunisation of teenagers has recently been removed from the immunisation schedule with a targeted strategy now recommended to immunise groups at increased risk in infancy or adulthood Pneumococcal conjugate vaccine was recommended for children under years with chronic lung renal liver and cardiac conditions diabetes immunosuppresion immunocompromised cochlear implants CSF shunts and previous invasive pneumococcal disease Conjugate vaccine produces a better immune response than polysaccharide vaccine in young children and has now been included in the routine vaccination schedule MMR is indicated for post- exposure prophylaxis within days of exposure to measles as the antibody response to the vaccine is faster than the response to natural infection Individuals at high risk of severe illness should receive human normal immunoglobulin Varicella vaccine is not currently recommended in the UK for universal childhood immunisation but it is recommended for non-immune close contacts of immunocompromised patients and non-immune health care workers Palivizumab is recommended for speci ?c groups at risk of severe RSV disease although these individuals represent a very small fraction of the health burden of RSV Currently use in children under years with chronic lung disease requiring oxygen is recommended but use in those with chronic lung disease not requiring oxygen requires more evidence Group B streptococcus GBS Streptococcus agalactiae is the commonest cause of severe early onset within days of birth infection in new born infants About of mothers in the UK are carriers and the incidence of proven neonatal disease is about live births Universal screening and intrapartum intravenous antibiotic prophylaxis is practised in the United States and has resulted in a decrease in the incidence of early onset neonatal infection with GBS but has not clearly demonstrated a decrease in neonatal deaths and there are concerns about antibiotic resistance and other organisms replacing GBS infection GBS is one of the most common causes of early onset neonatal meningitis but recent studies show that the incidence appears to be declining probably as a result of antibiotic prophylaxis policies Blood cultures are probably negative in more than half of cases of probable GBS infection due to antibiotic prophylaxis or insu ?cient samples of blood Late onset GBS infection after week of age is well described and accounts for about one-third of all cases Diseases noti ?able by law di ?er between the three areas of England Wales Northern Ireland and Scotland Generally speaking the diseases against which routine immunisation